Sharmishtha Shyamal

My research lies at the intersection of RNA biology and reproductive health. I am particularly interest-ed in how non-coding RNAs (ncRNAs) interact with coding transcripts to fine-tune gene expression in the endometrium, especially during the critical window of implantation. By exploring these regulatory networks, my work aims to uncover the molecular basis of reproductive dysfunctions such as recurrent implantation failure (RIF) and recurrent pregnancy loss (RPL). A core focus of my research is the development of non-invasive biomarkers to assess endometrial re-ceptivity, using liquid biopsy approaches. To this end, I integrate transcriptomic profiling with chro-matin mapping and computational analysis to decode RNA-driven regulatory programs that shape en-dometrial function. My work has contributed to the understanding of circular RNA–mRNA interac-tions and their role in post-transcriptional gene regulation, particularly in the context of epithelial plasticity during implantation. Looking ahead, I am working towards integrating multi-omics data to enable precision diagnostics and targeted interventions in reproductive medicine. My long-term goal is to bridge molecular insights with clinical application, ultimately improving outcomes in assisted reproduction and advancing wom-en's health.