Diya Binoy Joseph

I am an independent investigator and faculty member at DBT-inStem with more than 9 years of experience in cell and molecular biology and 9 research articles spanning independent and collaborative projects. I have demonstrated experience in scientific communication with 4 review articles, 1 book chapter and several invited talks. I am passionate about science education, having mentored 10 students at the undergraduate and graduate level. I completed my PhD from the University of Wisconsin-Madison. My award winning PhD research was on development of the lower urinary tract with creative utilization of genetic mouse models, tissue recombination, imaging and RNA sequencing. After my PhD training, I completed my postdoctoral fellowship at UT Southwestern Medical Centre as an American Urological Association Research Scholar working on cellular plasticity in Benign prostatic hyperplasia utilizing single cell RNA-sequencing and spatial transcriptomics to understand treatment resistance in patients. At inStem, I am working at the interface of cell biology and translational research to study the epithelial-mesenchymal interactions that pattern the developing genitourinary tract. I am also studying how early differentiation of the genitourinary tract influences the establishment of the resident immune niche with implications for host defense in the adult. My lab works with mouse and cell culture models to understand novel aspects of genitourinary tract development. My lab's research is supported by the India Alliance Early career fellowship and the SERB start-up grant along with generous support by DBT-inStem.