Chinmoy Patra

Research Interest: The development of an organ or new life is a spectacular process that is controlled by spatiotemporal gene expression. My lab is interested in understanding how extracellular matrix (ECM) molecules and adhesion G-protein coupled receptors (aGPCRs) are involved in organ development, tissue homeostasis, organ function, and regeneration at the cellular level, using zebrafish as a model organism. We investigate our questions utilizing genetic (transgenesis, genome editing with the help of state-of-the-art technology TALEN and CRISPR-Cas) and pharmacological approaches. One of our goals is to understand the crosstalk between different cell types via ECM components in cardiovascular development and regeneration. Research Keywords: cardiovascular biology, developmental biology, regenerative biology, zebrafish