What is your area of work and what led you to take up a career in research?
I am currently a postdoctoral researcher at the Gladstone Institutes, UCSF, focusing on cardiac development and regeneration. My journey into research began with a deep fascination for the complex signaling pathways that govern cellular processes. During my doctoral research under the guidance of Prof. Anu Rangarajan and Prof. Ramray Bhat at IISc, Bangalore, I delved into the role of AMP-activated protein kinase (AMPK) in mammary alveolar growth and lactogenic differentiation. This experience solidified my interest in uncovering intricate biological mechanisms and inspired me to delve into cardiovascular research, aiming to unravel novel therapeutic targets for heart diseases, driven by a desire to make impactful contributions to human health.
What are your current research interests?
My current research interests revolve around understanding the genetic and molecular mechanisms underlying cardiomyocyte proliferation and regeneration in the adult heart. By leveraging cutting-edge technologies such as single-cell RNA sequencing and CRISPR/Cas9 gene editing, I aim to identify key genes and pathways that are crucial for cardiac development and regeneration. This research holds the potential to offer new therapeutic avenues for treating cardiovascular diseases, making it an exciting and impactful field to work in.
What keeps you going/what excites you the most right now?
The thrill of discovery and the potential to make a significant impact on human health is what drives me the most. The possibility of uncovering novel pathways that could lead to groundbreaking treatments for cardiovascular diseases is incredibly exciting. Additionally, mentoring students and junior researchers adds a deeply fulfilling dimension to my work. Working in a collaborative and innovative environment at the Gladstone Institutes, surrounded by passionate scientists, keeps me motivated and inspired every day.
How did you get to know about InSDB and what made you join as a member?
I learned about InSDB through my colleagues and the broader scientific community. The society’s commitment to fostering scientific dialogue and collaboration, particularly in the field of developmental biology, resonated strongly with my own research goals and interests. Joining InSDB has provided me with invaluable opportunities to network with fellow researchers, share my work, and stay updated on the latest advancements in the field.
Is there any particular initiative that you would like InSDB to start?
I would love to see InSDB initiate more mentorship programs that connect early-career researchers with established scientists. Such programs can provide guidance, support, and career development opportunities, which are crucial for young researchers navigating their career paths. Additionally, workshops focused on advanced research techniques and grant writing would be highly beneficial and enhance the skill sets of researchers at various stages of their careers.
As a post-doc right now, are there any tips that you’d want to let PhD graduates know?
Absolutely. My advice to PhD graduates is to stay curious and resilient. Research can be challenging, but persistence and a positive mindset are key to overcoming obstacles. Seek out interdisciplinary collaborations, as they can open up new avenues for your research and broaden your perspective. Also, do not hesitate to reach out for mentorship and be proactive in your career development by attending workshops and networking events. These activities can significantly enhance your professional growth and opportunities.
What are your plans going forward?
My long-term goal is to establish and lead an independent research group focused on cardiovascular development and disease. I aim to integrate anatomical, physiological, and developmental studies to uncover the underlying causes of cardiovascular diseases and develop new therapeutic strategies. In the short term, I plan to continue my postdoctoral research, engage in mentorship programs, and actively participate in scientific conferences to share my findings and collaborate with peers.
What do you do in your free time or what is a fun fact that people do not know about you?
In my free time, I love traveling to new places and experiencing different cultures. Whether it’s a bustling city or a serene countryside, I find joy in exploring new environments and meeting new people. A fun fact that many might not know about me is that I am always up for a sports challenge, whether it’s a friendly game of badminton, a competitive swim race, or any other sport that comes my way.
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You can connect with Shyam here.
